Thomas Brännström Selected Research

Superoxide Dismutase-1

1/2021	Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice.
1/2019	Misfolded SOD1 inclusions in patients with mutations in C9orf72 and other ALS/FTD-associated genes.
1/2019	The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension.
12/2018	Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis.
1/2016	Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease.
4/2015	Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping.
3/2013	Composition of soluble misfolded superoxide dismutase-1 in murine models of amyotrophic lateral sclerosis.
1/2013	Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis.
6/2011	Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice.
5/2011	Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis.

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Thomas Brännström Research Topics

Disease

28	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 01/2004
9	Glioma (Gliomas) 01/2022 - 08/2002
8	Neoplasms (Cancer) 01/2017 - 08/2002
5	Astrocytoma (Pilocytic Astrocytoma) 01/2022 - 08/2002
4	Oligodendroglioma 01/2022 - 08/2004
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 02/2002
3	Glioblastoma (Glioblastoma Multiforme) 08/2010 - 08/2002
2	Inflammation (Inflammations) 04/2014 - 05/2002
2	Meningioma (Meningiomas) 07/2012 - 08/2004
2	Necrosis 11/2002 - 08/2002
1	Gliosarcoma 01/2022
1	Lung Neoplasms (Lung Cancer) 08/2015
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2015
1	Malignant Mesothelioma 08/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 04/2014
1	Alzheimer Disease (Alzheimer's Disease) 04/2014
1	Amyloid Plaque 04/2014
1	Proteostasis Deficiencies 01/2014
1	Neuroinflammatory Diseases 03/2013
1	Multiple Sclerosis 03/2013
1	Brain Neoplasms (Brain Tumor) 07/2012
1	Parkinson Disease (Parkinson's Disease) 03/2012
1	Pituitary Neoplasms (Pituitary Adenoma) 04/2010
1	Breast Neoplasms (Breast Cancer) 02/2009
1	Peripheral Nerve Injuries 01/2007
1	Wounds and Injuries (Trauma) 01/2007
1	Motor Neuron Disease (Primary Lateral Sclerosis) 12/2006
1	Nausea 07/2006
1	Cataract (Cataracts) 12/2005
1	Stroke (Strokes) 09/2004
1	Hypoxia (Hypoxemia) 08/2002
1	Hypersensitivity (Allergy) 05/2002
1	Hyperoxia 05/2002
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 02/2002

Drug/Important Bio-Agent (IBA)

17	Superoxide Dismutase-1IBA 01/2021 - 01/2004
12	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2002
8	Superoxide DismutaseIBA 12/2018 - 05/2002
4	Superoxides (Superoxide)IBA 03/2013 - 12/2005
3	Biomarkers (Surrogate Marker)IBA 12/2019 - 09/2015
3	AntibodiesIBA 04/2014 - 03/2013
2	Serotonin (5 Hydroxytryptamine)IBA 01/2022 - 03/2012
2	PrionsIBA 01/2020 - 01/2016
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2017 - 07/2010
2	Nerve Growth Factors (Neurotrophins)IBA 12/2016 - 01/2014
2	Amyloid (Amyloid Fibrils)IBA 04/2014 - 01/2014
2	Biological ProductsIBA 04/2010 - 11/2002
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2005 - 05/2002
2	ZincIBA 12/2005 - 07/2004
2	CopperIBA 12/2005 - 07/2004
1	Amino Acids FDA Link 01/2022
1	2-Aminoadipic Acid (2 Aminoadipic Acid)IBA 01/2022
1	N-acetylaspartate (N-acetyl aspartate)IBA 01/2022
1	Hydroxyindoleacetic AcidIBA 01/2022
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Protein AggregatesIBA 08/2015
1	ceramide glucosyltransferaseIBA 08/2015
1	CeramidesIBA 08/2015
1	Cisplatin (Platino)FDA LinkGeneric 08/2015
1	globotriaosylceramide (globotriosylceramide)IBA 08/2015
1	Calgranulin BIBA 04/2014
1	Peptides (Polypeptides)IBA 01/2014
1	Natalizumab (Tysabri)FDA Link 03/2013
1	Progesterone Receptors (Progesterone Receptor)IBA 07/2012
1	Estrogen ReceptorsIBA 07/2012
1	Serotonin ReceptorsIBA 03/2012
1	Dopamine (Intropin)FDA LinkGeneric 03/2012
1	Protein Isoforms (Isoforms)IBA 07/2011
1	Laminin (Merosin)IBA 07/2011
1	Epidermal Growth Factor (EGF)IBA 08/2010
1	GonadotropinsIBA 04/2010
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2009
1	ProteomeIBA 06/2009
1	Bacterial ToxinsIBA 02/2009
1	Acetylcarnitine (Alcar)IBA 01/2007
1	Estramustine FDA Link 07/2006
1	Phosphates (Orthophosphate)IBA 07/2006
1	Glucose (Dextrose)FDA LinkGeneric 12/2005
1	Apoptosis Regulatory ProteinsIBA 09/2004
1	Messenger RNA (mRNA)IBA 08/2004
1	ErbB Receptors (EGF Receptor)IBA 08/2004
1	bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA 11/2002
1	DNA (Deoxyribonucleic Acid)IBA 11/2002
1	Eosine Yellowish-(YS) (Eosin)IBA 11/2002
1	Hematoxylin (Haematoxylon)IBA 11/2002
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2002
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 08/2002
1	EndotoxinsIBA 05/2002
1	ZymosanIBA 05/2002
1	EnzymesIBA 05/2002
1	Interleukin-5 (Interleukin 5)IBA 05/2002
1	OvalbuminIBA 05/2002
1	CytokinesIBA 05/2002
1	polyglutamineIBA 02/2002
1	Ataxin-7IBA 02/2002

Therapy/Procedure

3	Radiotherapy 01/2017 - 08/2002
2	Therapeutics 01/2022 - 01/2022
1	Catheters 01/2017
1	Lenses 12/2005